By Jonathan Gillard, Dr Martin Graves, Thomas Hatsukami, Chun Yuan
Stroke is an incredible explanation for morbidity and mortality, with carotid sickness representing an enormous contributory hazard issue. This e-book deals finished insurance of the pathogenesis and administration of carotid ailment with particular specialize in the position imaging has to play within the early reputation of symptomatic and asymptomatic disorder in addition to the therapy of the constructed . Technological advances in imaging modalities now permit precise research of the illness development, the prediction of serious occasions resulting in a stroke, in addition to the id of the best surgical or different interventional remedies. This e-book may be learn by way of neurologists, cardiologists, vascular surgeons, neurosurgeons and radiologists desirous about the care of sufferers with carotid illness, and likewise through researchers concerned with the advance of recent healing suggestions and drugs.Stroke is an immense reason behind morbidity and mortality, with carotid affliction representing an enormous contributory threat issue. This booklet deals finished insurance of the pathogenesis and administration of carotid affliction with particular concentrate on the position imaging has to play within the early acceptance of symptomatic and asymptomatic illness in addition to the remedy of the built . It discusses the technological advances in imaging modalities which now permit precise research of the disorder development, the prediction of serious occasions resulting in a stroke, in addition to the identity of the simplest surgical or different interventional remedies. hugely illustrated all through with prime specialist participants, this booklet could be learn through neurologists, cardiologists, vascular surgeons, neurosurgeons and radiologists all for the care of sufferers with carotid illness, and in addition via researchers desirous about the advance of latest healing concepts and medication.
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Extra resources for Carotid Disease: The Role of Imaging in Diagnosis and Management
Gore and Associates, Inc. Lectureship. The clinical and pathological spectrum of recurrent carotid steno- Intraplaque hemorrhage and progression of coronary atheroma. New England Journal of Medicine, 349, 2316À25. Mann, J. and Davies, M. J. (1999). Mechanisms of progression in native coronary artery disease: role of healed plaque disruption. Heart, 82, 265À8. , Glagov, S. and Zarins, C. K. (1994). Quantitative morphologic study of intimal thickening at the human carotid bifurcation: I. Axial and circumferential distribution of maximum intimal thickening in asymptomatic, uncomplicated 107, 137À46.
Imaging techniques for detection of vasa vasorum in carotid plaques may be important in future evaluation of carotid stenosis. 4 Fibrous cap, carotid atherosclerosis. These photographs of carotid plaques (Masson trichrome stain) demonstrate multiple necrotic cores (NC), with a fibrin-rich central area, and a thin fibrous cap (arrow) with collagen staining blue (A). Panel B shows a single large necrotic core, with a thicker fibrous cap than shown in panel A (arrow). 5 Plaque hemorrhage within a necrotic core.
1994, 1995). More recently, there has been focus on the concept of vulnerability of atherosclerotic plaques to rupture and lead to atherothrombotic sequellae, such as stroke for plaque rupture in the carotid arteries or myocardial infarction for plaque rupture in the coronary arteries Carotid Disease: The Role of Imaging in Diagnosis and Management, ed. Jonathan Gillard, Martin Graves, Thomas Hatsukami and Chun Yuan. Published by Cambridge University Press. ß Cambridge University Press 2007. , 2003a,b).